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Jabfrit News….
Skin cancer vaccine stops relapse in trial breakthrough Personalised mRNA jab tells immune system to hunt down melanoma tumours
Telegraph Reporters Published 19 August 2026 8:26pm BST A personalised vaccine for skin cancer can help stop the spread of the disease, according to a leading drug manufacturer.
Moderna, the US pharmaceutical company, announced positive results for the world’s first personalised mRNA cancer jab for melanoma in an investor update on Wednesday.
It said interim results for the vaccine, called Intismeran, showed reduced recurrence of the cancer and also stopped the disease from spreading to other parts of the body.
The drug was given to people with high-risk melanoma after they had surgery and the results have been hailed as a “landmark moment” in personalised cancer treatment.
The vaccine is custom-built for each patient in a few weeks and works by telling the body’s immune system to hunt down cancer cells and prevent the disease from coming back.
Prof Georgina Long, medical director of Melanoma Institute Australia and the study’s principal investigator, said: “Today’s results represent a landmark moment for adjuvant melanoma treatment.”
Results from the phase-three trial of more than 1,000 patients show the vaccine, in combination with MSD’s immunotherapy Keytruda medicine, almost halved the risk of recurrence in patients.
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